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C.CaoZ.et al (2010)

In mice, GLP-1/dexa reduced the expression of reward-related genes in the NAc such as D1R, dopamine receptor 2 long isoform (D2rlg), kappa opioid receptor (Kor), glucocorticoid receptor (Gr), others such as TH and dopamine transporter (DAT) were also decreased but non-significantly (Decarie-Spain et al., 2019)

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure, according to the updated Ozempic label

June 2020